technologies are attractive for diagnosing cancer and for
monitoring cancer therapy because these techniques are inexpensive,
portable, fast and provide a wealth of information on tissue structure
and function. Dr. Skala's lab focuses on the development of
optical imaging tools that monitor biological markers such as cellular
metabolic rate, molecular expression, blood oxygenation and
blood flow. These tools are applied to pre-clinical models
for the design and development of effective therapeutic strategies, and
in clinical studies to provide early detection and individualized
treatment to cancer patients. Specific technologies under
development include optical coherence tomography to monitor blood flow
and microvessel morphology, multiphoton and fluorescence lifetime
microscopy to image cellular metabolism, photothermal microscopy with
nanoparticle contrast agents for molecular imaging, and optical
spectroscopy to quantify tissue blood content and oxygenation.
to find us:
Optical Society of America:
Optics in Life Sciences Congress , 14-18 April, Kona, Hawaii
[MT3C.3] April 16, 2013 from 11:45AM to 12:00 PM
"A Novel Optical Metabolic Assay of Cancer Drug Efficacy in Primary 3D
A. Walsh, R.S. Cook, C.L. Arteaga, M.C. Skala
[MT3C.5] April 16, 2013 from 12:15PM to 12:30 PM
"Autofluorescence Imaging Resolves Early Cancer Treatment Response In
A. Walsh, R.S. Cook, H.C. Manning, D.J. Hicks, A. Lafontant, C.L.
Arteaga, M.C. Skala
[MTh2B.4] April 18, 2013 from 10:15 AM to 12:15 PM
"Full Range Photothermal Optical Coherence Tomography of Gold
J.M. Tucker - Schwartz; M.J. Schultis; K. Beavers; C. Duvall; M.C.
NSF Workshop on US-Czech
Frontiers in Photonics, 18-19 April, Prague, Czech Republic
"Optical Metabolic Imaging of Treatment Response in Head and Neck
A. Shah, M. Demory Beckler, A. Walsh, P. Pohlmann, M.C. Skala
Advances in Optics for
Biotechnology, Medicine and Surgery XIII, 2-5 June, Lake Tahoe,
"Optical Imaging of Vascular Remodeling and Blood Oxygenation After
Growth Factor Treatment in the Mouse Hind Limb Ischemia Model."
K.M. Poole, J.M. Tucker-Schwartz, C.A. Patil, C.E. Nelson, C.L. Duvall,
2013 This page is an
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